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CRHR2 Antibody

CHCR2, or Corticotropin releasing hormone receptor 2, is a receptor for CRH (corticotropin-releasing hormone), a neurotransmitter secreted by the hypothalamus in response to stress. There are three major isoforms of CHCR2: alpha, beta and gamma, differing in their N-terminus amino acid sequence. Isoform beta and gamma are expressed in the brain, with gamma expression highest in the septum and hippocampus, while alpha is expressed in the peripheral tissues of the brain.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 0.5-2 µg/mL

UniProt

Q13324

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A recombinant protein fragment from the N-terminal portion of human CRHR2 was used as the immunogen for this antibody (1) .

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Protein A affinity chromatography

Format

Purified

Buffer

1X PBS, pH 7.4

Reconstitution

Aliquot the CRHR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This CRHR2 antibody is available for research use only.

Storage Conditions

Aliquot the CRHR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Provided assay concentrations are suggestions only, CRHR2 antibody titration may be required for optimal results.</p>1. This antibody will detect the alpha (411 AA), beta (438 AA) and gamma (397 AA) isoforms of CRHR2.

Location

Membrane, Secreted

Image Legend

Western blot testing of human samples with CRHR2 antibody at 0.5ug/ml.

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