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PDLIM1 Antibody

PDLIM1 (PDZ And LIM Domain 1) is a member of the protein family Enigma and named for its amino terminal PDZ domain and carboxy terminal LIM domains. In breast cancer cells, PDLIM1 interacts with alpha actin 1 and 4, and is an important regulator of breast cancer cell migration and metastasis, but not proliferation. PDLIM1 is widely expressed, with high expression seen in muscle and heart, low expression in pancreas, thymus, liver and kidney, and no expression in testis, ovary and brain.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-3 µg/mL

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant protein fragment from human PDLIM1 was used as the immunogen for this antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Protein A affinity chromatography

Format

Purified

Buffer

1X PBS, pH 7.4

Reconstitution

Aliquot the antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PDLIM1 antibody is available for research use only.

Storage Conditions

Aliquot the antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

Image Legend

Western blot testing of human samples with PDLIM1 antibody at 1ug/ml.

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