GPR77 Antibody
G protein receptors, also called GPRs, GPCRs, and seven-transmembrane domain receptors, are a large family of receptors with possibly over 800 members. These receptors sense stimuli outside, convey the signal across the cell membrane, and activate internal signal transduction pathways and cellular responses. GPR77 is involved in the complement system of the innate immune response and may signal through the beta-arrestin pathway, and possibly act as a decoy receptor. It is co-expressed with the C5a receptor on neutrophils and may modulate C5a1 activity.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-3 µg/mL
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant protein fragment from the N-terminal region of human GPR77 was used as the immunogen for this antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Protein A Affinity Chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Aliquot the GPR77 antibody and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.
Limitations
This GPR77 antibody is available for research use only.
Storage Conditions
Aliquot the GPR77 antibody and store frozen at -20°C or colder to avoid repeated freeze-thaw cycles.
Formulation
0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Provided assay concentrations are suggestions only, GPR77 antibody titration may be required for optimal results.
Image Legend
Western blot testing of human samples using GPR77 antibody at 1ug/ml.
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