NKIRAS1 Antibody
NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions.<p>NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity.
Product Specifications
UniProt
Q9NYS0
Host
Mouse
Immunogen
A recombinant protein fragment from the central region of NKIRAS1 was used as the immunogen for this antibody.
Clonality
Monoclonal
Isotype
IgG1 κ
Applications
WB
Format
Purified
Buffer
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot the NKIRAS1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NKIRAS1 antibody is available for research use only.
CAS Number
9007-83-4
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