SGK1 Antibody
SGK1 (Serine/threonine-protein kinase 1) is a member of a serine/threonine subfamily of kinases. This kinase is involved in a wide variety of cellular functions including cell growth, survival and migration as well as a wide variety of cellular processes including transcription (Foxo3A, b-catenin, NF-kB, and p53), stress response and apoptosis. SGK1 also participates in neuronal function. Expression of SGK1 is stimulated by amphetamine, LSD and neuronal injury, it stimulates dendrite growth, is important in long term memory, fear-conditioning/spatial/novel object recognition learning and is likely involved in the pathophysiology of Alzheimer's disease.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-3 µg/mL
Host
Rabbit
Reactivity
Human
Immunogen
A recombinant protein fragment from the C-terminal region of human SGK1 was used as the immunogen for this antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Protein A affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Aliquot the SGK1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SGK1 antibody is available for research use only.
Storage Conditions
Aliquot the SGK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Image Legend
Western blot testing of human pancreas lysate with SGK1 antibody at 1ug/ml.
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