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TRIL Antibody / KIAA0644

TRIL or TLR4 interactor with leucine rich repeats, is a protein encoded by the human KIAA0644 gene. TRIL protein sequence is highly conserved across species. It is expressed in a number of tissues with highest expression in brain, ovary, small intestine and spleen. TRIL is an accessory molecule that interacts with TLR3 and endosomal TLR4, enhancing their interaction with their ligands, poly (I:C) and LPS, and increasing the production of type I interferons in the innate immune response.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 2-5 µg/mL

Host

Rabbit

Reactivity

Human

Immunogen

A recombinant protein fragment from the C-terminal region of human TRIL was used as the immunogen for this antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Protein A affinity chromatography

Format

Purified

Buffer

1X PBS, pH 7.4

Reconstitution

Aliquot the antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This TRIL antibody is available for research use only.

Storage Conditions

Aliquot the antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.

Image Legend

Western blot testing of human samples with TRIL antibody at 2ug/ml.

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