NQO1 Antibody
NAD(P)H:quinone oxidoreductase is an enzyme that catalyzes the two-electron reduction of quinones to hydroquinones, resulting in the activation or deactivation of the hydroquinone. Increased expression of NQO1 is seen in tumors of the breast, liver and colon and NSCLC (non-small cell lung cancer), suggesting a role in tumor development and possibly treatment. NQO1 has also been linked to Alzheimer's disease, found to be upregulated in response to the oxidative stress of the AD process.
Product Specifications
Host
Rabbit
Immunogen
A recombinant protein fragment from the C-terminal region of human NQO1 was used as the immunogen for this antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Format
Purified
Buffer
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NQO1 antibody is available for research use only.
CAS Number
9007-83-4
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