NQO1 Antibody
NAD (P) H:quinone oxidoreductase is an enzyme that catalyzes the two-electron reduction of quinones to hydroquinones, resulting in the activation or deactivation of the hydroquinone. Increased expression of NQO1 is seen in tumors of the breast, liver and colon and NSCLC (non-small cell lung cancer), suggesting a role in tumor development and possibly treatment. NQO1 has also been linked to Alzheimer's disease, found to be upregulated in response to the oxidative stress of the AD process.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1-3 µg/mL
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A recombinant protein fragment from the C-terminal region of human NQO1 was used as the immunogen for this antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Protein A affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Aliquot and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This NQO1 antibody is available for research use only.
Storage Conditions
Aliquot and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Provided assay concentrations are suggestions only, NQO1 antibody titration may be required for optimal results.
Image Legend
Western blot testing of human samples using NQO1 antibody at 1ug/ml. Predicted molecular weight ~30kDa.
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