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Neurotensin Receptor 2 Antibody

Neurotensin is a central nervous system protein involved with the regulation and release of Luteinizing hormone (Lutropin), which regulates ovulation in females and testosterone production in males, and Prolactin (Luteotropin), which enables milk production in female mammals. The GPCR Neurotensin receptor 2 (NTSR2) is one of three receptors for Neurotensin (NTSR1-3) . Unlike NTSR1, NTSR2 has only a low affinity for Neurotensin, but high affinity for levocabastine, a histamine H1 receptor antagonist that can block Neurotensin binding to NTSR2 but not affect its binding to NTSR1.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-3 µg/mL

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A recombinant protein fragment from the N-terminal half of human Neurotensin Receptor 2 was used as the immunogen for this antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Protein A purified antibody

Format

Purified

Buffer

1X PBS, pH 7.4

Reconstitution

Aliquot the Neurotensin Receptor 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Neurotensin Receptor 2 antibody is available for research use only.

Storage Conditions

Aliquot the Neurotensin Receptor 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide

Applications Notes

Provided assay concentrations are suggestions only, Neurotensin Receptor 2 antibody titration may be required for optimal results.

Image Legend

Western blot testing of human samples with Neurotensin Receptor 2 antibody at 0.5ug/ml.

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