UNC93B Antibody
UNC93B is part of the innate immune response via its direct interaction with the intracellular toll-like receptors TLR3, 7, and 9. UNC93B aids in the trafficing of these TLRs from the ER to the endolysosomes, where they bind ligands and initiate immune response. In the absence of UNC93B, these TLRs are unable to respond to foreign stimuli.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 3-6 µg/mL
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog
Immunogen
A recombinant protein fragment from the C-terminal portion of UNC93B was used as the immunogen for this antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Protein A Affinity Chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Aliquot the antibody and store frozen at -20oC or colder to avoid repeated freeze-thaw cycles.
Limitations
This UNC93B antibody is available for research use only.
Storage Conditions
Aliquot the antibody and store frozen at -20°C or colder to avoid repeated freeze-thaw cycles.
Formulation
0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Image Legend
Western blot testing of human samples with UNC93B antibody at 3ug/ml.
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