SPIB Antibody
SPIB is a transcription factor in the Ets family. It is found in lymphoid cells and not in monocytes or myeloid cells. SPIB is a regulator of pDC development via its interaction with ID2, E2-2 and BCL2-A1. It promotes E2-2 activity and suppresses Id2 expression to enhance pDC development. It also promotes pDC survival by activation of the antiapoptotic gene BCL2-A1.
Product Specifications
Host
Rabbit
Immunogen
A recombinant protein fragment from the C-terminal half of SPIB was used as the immunogen for this antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Format
Purified
Buffer
0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Aliquot and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SPIB antibody is available for research use only.
CAS Number
9007-83-4
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