Syndecan 4 Antibody
Syndecans are a family of four transmembrane proteoglycans divided into two subfamilies based on transmembrane and cytoplasmic domain similarity: Syndecan 1/3 and 2/4. Via their covalently attached heparan sulphate chains, they bind a variety of ligands and play a role in a number of cell functions including adhesion, proliferation and migration. Syndecan 4 is highly expressed on the cell surface of epithelial cells and fibroblasts and plays an important role in tissue repair. Integrin-mediated binding of fibronectin to Syndecan-4 induces focal adhesions and formation of cytoskeletal stress fibers, facilitating wound healing.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 2-5 µg/mL
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A recombinant protein fragment from the N-terminal region of human Syndecan 4 was used as the immunogen for this antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB
Purity
Protein A affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Aliquot the Syndecan 4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Syndecan 4 antibody is available for research use only.
Storage Conditions
Aliquot the Syndecan 4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Image Legend
Western blot testing of human samples with Syndecan 4 antibody at 2ug/ml.
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