MAP3K13 Antibody

Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:250-1:500, Immunofluorescence: 1:50-1:100

UniProt

O43283

Host

Mouse

Reactivity

Human

Immunogen

A portion of amino acids 52-305 from the human protein was used as the immunogen for the MAP3K13 antibody.

Clonality

Monoclonal

Isotype

IgM

Clone

810CT26.6.1.1

Applications

WB, IF

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the MAP3K13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This MAP3K13 antibody is available for research use only.

Storage Conditions

Aliquot the MAP3K13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the MAP3K13 antibody may be required due to differences in protocols and secondary/substrate sensitivity.