MAP3K13 Antibody
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:250-1:500, Immunofluorescence: 1:50-1:100
UniProt
O43283
Host
Mouse
Reactivity
Human
Immunogen
A portion of amino acids 52-305 from the human protein was used as the immunogen for the MAP3K13 antibody.
Clonality
Monoclonal
Isotype
IgM
Clone
810CT26.6.1.1
Applications
WB, IF
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the MAP3K13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MAP3K13 antibody is available for research use only.
Storage Conditions
Aliquot the MAP3K13 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic
Image Legend
Immunofluorescent staining of human NCI-H460 cells with MAP3K13 antibody (green), DAPI nuclear stain (blue) and anti-Actin (red) .
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