FANCC Antibody / Fanconi anemia group C protein
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2) . The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This protein is for complementation group C.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:1000, Immunofluorescence: 1:25, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:50-1:100
UniProt
Q00597
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 527-555 from the human protein was used as the immunogen for the FANCC antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IF, FACS, IHC-P
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the FANCC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This FANCC antibody is available for research use only.
Storage Conditions
Aliquot the FANCC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic, nuclear
Image Legend
Western blot testing of human 1) HepG2 and 2) HL60 cell lysate with FANCC antibody. Predicted molecular weight ~63 kDa.
Documents
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