XDH Antibody / Xanthine Oxidase
XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. This protein can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:1000, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:10-1:50
UniProt
P47989
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 206-234 from the human protein was used as the immunogen for the XDH antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, IHC-P
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the XDH antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This XDH antibody is available for research use only.
Storage Conditions
Aliquot the XDH antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic, secreted
Image Legend
Western blot testing of human fetal liver tissue lysate with XDH antibody. Predicted molecular weight ~146 kDa.
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