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Mu-type Opioid Receptor Antibody / OPRM1 / MOR-1

OPRM1 is the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin and the enkephalins. The OPRM1 receptor is a membrane of the G protein-coupled receptor family (Bond et al., 1998) . There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:1000, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:10-1:50

UniProt

P35372

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 161-187 from the human protein was used as the immunogen for the Mu-type Opioid Receptor antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, FACS, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Mu-type Opioid Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Mu-type Opioid Receptor antibody is available for research use only.

Storage Conditions

Aliquot the Mu-type Opioid Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Mu-type Opioid Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

Western blot testing of mouse heart tissue lysate with Mu-type Opioid Receptor antibody. Predicted molecular weight ~45 kDa.

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