ADAMTS18 Antibody

ADAMTS18 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. This protein has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1:25 (1x10e6 cells), Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25

UniProt

Q8TE60

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 1066-1095 from the human protein was used as the immunogen for the ADAMTS18 antibody.

Clonality

Polyclonal

Isotype

Applications

FACS, WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the ADAMTS18 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This ADAMTS18 antibody is available for research use only.

Storage Conditions

Aliquot the ADAMTS18 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the ADAMTS18 antibody may be required due to differences in protocols and secondary/substrate sensitivity.