PFKM Antibody / Fructose 6 Phosphate Kinase
Phosphofructokinase catalyzes the irreversible conversion of fructose 6 phosphate to fructose 1,6 bisphosphate. Mammalian PFK is a complex isozyme consisting of 3 subunits: muscle (M), liver (L), and platelet (P) . Only M type PFK isozyme is expressed in mature muscle, while erythrocytes contain both L and M subunits. Defects in PFKM are the cause of glycogen storage disease type 7 (GSD7), also known as Tarui disease.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:10-1:50, Immunohistochemistry (FFPE) : 1:50-1:100, Western blot: 1:500-1:1000
UniProt
P08237
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 746-776 from the human protein was used as the immunogen for the PFKM antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, IHC-P, WB
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PFKM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PFKM antibody is available for research use only.
Storage Conditions
Aliquot the PFKM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic
Image Legend
Western blot testing of human HeLa cell lysate with PFKM antibody. Predicted molecular weight ~85 kDa.
Documents
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Biliverdin Reductase (BLVRA) Rabbit Polyclonal Antibody
C1QB / Complement C1q B-Chain (C1QB/2965), CF405S conjugate, 0.1mg/mL
SOX2 (Embryonic Stem Cell Marker) (SOX2/3169R), CF405S conjugate, 0.1mg/mL
6-(tert-Butylamino)-1,3,5-triazine-2,4(1H,3H)-dione
