PI3K delta Antibody / PI3KCD / p110 delta

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunofluorescence: 1:10-1:50, Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:50-1:100

UniProt

O00329

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 687-717 from the human protein was used as the immunogen for the PI3K delta antibody.

Clonality

Polyclonal

Isotype

Applications

IF, WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the PI3K delta antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PI3K delta antibody is available for research use only.

Storage Conditions

Aliquot the PI3K delta antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the PI3K delta antibody may be required due to differences in protocols and secondary/substrate sensitivity.