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FKBP1B Antibody

FKBP1B is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. The protein is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunofluorescence: 1:10-1:50, Immunohistochemistry (FFPE) : 1:10-1:50, Western blot: 1:500-1:1000

UniProt

P68106

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 16-46 from the human protein was used as the immunogen for the FKBP1B antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IF, IHC-P, WB

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the FKBP1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This FKBP1B antibody is available for research use only.

Storage Conditions

Aliquot the FKBP1B antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the FKBP1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human HEK293 cell lysate with FKBP1B antibody. Predicted molecular weight ~12 kDa.

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