GSN Antibody / Gelsolin

GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this protein are a cause of familial amyloidosis Finnish type (FAF) .

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000-1:2000, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:50-1:100

UniProt

P06396

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A portion of amino acids 230-259 from the human protein was used as the immunogen for the GSN antibody.

Clonality

Polyclonal

Isotype

Applications

WB, FACS, IHC-P

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the GSN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This GSN antibody is available for research use only.

Storage Conditions

Aliquot the GSN antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the GSN antibody may be required due to differences in protocols and secondary/substrate sensitivity.