SORBS2 Antibody / ARGBP2
Arg and c-Abl represent the mammalian members of the Abelson family of non-receptor protein-tyrosine kinases. They interact with the Arg/Abl binding proteins via the SH3 domains present in the carboxy end of the latter group of proteins. ARGBP2 is the sorbin and SH3 domain containing 2 protein. It has three C-terminal SH3 domains and an N-terminal sorbin homology (SoHo) domain that interacts with lipid raft proteins. The subcellular localization of this protein in epithelial and cardiac muscle cells suggests that it functions as an adapter protein to assemble signaling complexes in stress fibers, and that it is a potential link between Abl family kinases and the actin cytoskeleton.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:1000, Immunofluorescence: 1:10-1:50, Immunohistochemistry (FFPE) : 1:10-1:50, Flow cytometry: 1:10-1:50 (1x10e6 cells)
UniProt
O94875
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 175-204 from the human protein was used as the immunogen for the SORBS2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IF, IHC-P, FACS
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SORBS2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SORBS2 antibody is available for research use only.
Storage Conditions
Aliquot the SORBS2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Frequently Asked Questions
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