FPGS Antibody / Folylpolyglutamate synthase

FPGS is the folylpolyglutamate synthetase enzyme. This enzyme has a central role in establishing and maintaining both cytosolic and mitochondrial folylpolyglutamate concentrations and, therefore, is essential for folate homeostasis and the survival of proliferating cells. This enzyme catalyzes the ATP-dependent addition of glutamate moieties to folate and folate derivatives.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:50-1:100, Western blot: 1:500-1:1000

UniProt

Q05932

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 304-330 from the human protein was used as the immunogen for the FPGS antibody.

Clonality

Polyclonal

Isotype

Applications

FACS, IHC-P, WB

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the FPGS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This FPGS antibody is available for research use only.

Storage Conditions

Aliquot the FPGS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the FPGS antibody may be required due to differences in protocols and secondary/substrate sensitivity.