Ferritin heavy chain Antibody / FTH1

FTH1 is the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:50-1:100, Western blot: 1:500-1:1000

UniProt

P02794

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 154-183 from the human protein was used as the immunogen for the Ferritin heavy chain antibody.

Clonality

Polyclonal

Isotype

Applications

FACS, IHC-P, WB

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Ferritin heavy chain antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Ferritin heavy chain antibody is available for research use only.

Storage Conditions

Aliquot the Ferritin heavy chain antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Ferritin heavy chain antibody may be required due to differences in protocols and secondary/substrate sensitivity.