Espin Antibody / ESPN

ESPN is a multifunctional actin-bundling protein. It plays a major role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction in various mechanosensory and chemosensory cells.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:50-1:100, Western blot: 1:500-1:1000

UniProt

B1AK53

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 17-45 from the human protein was used as the immunogen for the Espin antibody.

Clonality

Polyclonal

Isotype

Applications

FACS, IHC-P, WB

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Espin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Espin antibody is available for research use only.

Storage Conditions

Aliquot the Espin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Espin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

Western blot testing of human SK-BR-3 cell lysate with Espin antibody. Predicted molecular weight ~92 kDa; isoforms can be observed at ~110 kDa and ~30 kDa.