TAGLN Antibody / Transgelin / SM22 alpha

TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1:10-1:50 (1x10e6 cells), Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:50-1:100

UniProt

Q01995

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 24-51 from the human protein was used as the immunogen for the TAGLN antibody.

Clonality

Polyclonal

Isotype

Applications

FACS, WB, IHC-P

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the TAGLN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This TAGLN antibody is available for research use only.

Storage Conditions

Aliquot the TAGLN antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the TAGLN antibody may be required due to differences in protocols and secondary/substrate sensitivity.