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KLF11 Antibody / TIEG2

TIEG2 is a transcription factor. The protein activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth. It represses transcription of SMAD7 which enhances TGF-beta signaling. It induces apoptosis.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1:50-1:100, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunofluorescence: 1:10-1:50, Western blot: 1:500-1:1000

UniProt

O14901

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 7-36 from the human protein was used as the immunogen for the KLF11 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC-P, FACS, IF, WB

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the KLF11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This KLF11 antibody is available for research use only.

Storage Conditions

Aliquot the KLF11 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the KLF11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Nuclear

Image Legend

Western blot testing of human K562 cell lysate with KLF11 antibody. Expected molecular weight: 55-65 kDa.

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