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DCN Antibody / Decorin

DCN is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1:10-1:50, Flow cytometry: 1:10-1:50 (1x10e6 cells), Western blot: 1:500-1:1000

UniProt

P07585

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 122-150 from the human protein was used as the immunogen for the DCN antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

IHC-P, FACS, WB

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the DCN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This DCN antibody is available for research use only.

Storage Conditions

Aliquot the DCN antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the DCN antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Flow cytometry testing of human HepG2 cells with DCN antibody; Blue=isotype control, Green= DCN antibody.

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