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OASIS Antibody / CREB3L1

CREB3L1 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. It is specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity) . It may play a role in gliosis. In vitro, it binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1:50-1:100, Flow cytometry: 1:10-1:50 (1x10e6 cells), Western blot: 1:2000-1:8000

UniProt

Q96BA8

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 481-509 from the human protein was used as the immunogen for the OASIS antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC-P, FACS, WB

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the OASIS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This OASIS antibody is available for research use only.

Storage Conditions

Aliquot the OASIS antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the OASIS antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic, nuclear

Image Legend

Western blot testing of human HepG2 cell lysate with OASIS antibody. Predicted molecular weight ~57 kDa. The ~47 kDa isoform may also be visualized.

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