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Interleukin-1 Receptor Antagonist Antibody / IL1RA / IL1RN

The protein is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. A polymorphism of its gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:1000, Immunofluorescence: 1:10-1:50, Flow cytometry: 1:10-1:50 (1x10e6 cells)

UniProt

P18510

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 147-177 from the human protein was used as the immunogen for the Interleukin-1 Receptor Antagonist antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IF, FACS

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Interleukin-1 Receptor Antagonist antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Interleukin-1 Receptor Antagonist antibody is available for research use only.

Storage Conditions

Aliquot the Interleukin-1 Receptor Antagonist antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Interleukin-1 Receptor Antagonist antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

Western blot testing of human 1) HEK293 and 2) HeLa cell lysate with Interleukin-1 Receptor Antagonist antibody. Predicted molecular weight ~20 kDa.

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