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Calcipressin-2 Antibody / RCAN2 / DSCR1L1

Calcipressin-2/DSCR1L1 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. This protein may play a role during central nervous system development. Expression is detected in fibroblasts, heart, brain, liver, and skeletal muscle but not in placenta, lung, kidney and pancreas. Expression of both transcripts is upregulated by physiologic concentrations of the thyroid hormone triiodothyroxine.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:10-1:50, Western blot: 1:500-1:1000

UniProt

Q14206

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 6-37 from the human protein was used as the immunogen for the Calcipressin-2 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

FACS, IHC-P, WB

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Calcipressin-2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Calcipressin-2 antibody is available for research use only.

Storage Conditions

Aliquot the Calcipressin-2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Calcipressin-2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic, nuclear

Image Legend

Western blot testing of mouse heart tissue lysate with Calcipressin-2 antibody. Predicted molecular weight ~22 kDa.

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