Major Vault Protein Antibody / MVP
MVP, the major vault protein, is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1:10-1:50, Flow cytometry: 1:10-1:50 (1x10e6 cells), Western blot: 1:500-1:1000
UniProt
Q14764
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 863-893 from the human protein was used as the immunogen for the Major Vault Protein antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, FACS, WB
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Major Vault Protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Major Vault Protein antibody is available for research use only.
Storage Conditions
Aliquot the Major Vault Protein antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic, nuclear
Image Legend
Documents
Frequently Asked Questions
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