Beta-secretase 1 Antibody / Memapsin-2 / BACE1C
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the BACE1. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi.
Product Specifications
UniProt
P56817
Host
Rabbit
Immunogen
A portion of amino acids 125-154 from the human protein was used as the immunogen for the Beta-secretase 1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, FACS, WB
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Beta-secretase 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Beta-secretase 1 antibody is available for research use only.
CAS Number
9007-83-4
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