Lymphocyte Specific Protein 1 Antibody / LSP1

LSP1 / Lymphocyte Specific Protein 1 is an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:50-1:100, Western blot: 1:2000-1:8000

UniProt

P33241

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 108-134 from the human protein was used as the immunogen for the Lymphocyte Specific Protein 1 antibody.

Clonality

Polyclonal

Isotype

Applications

FACS, IHC-P, WB

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Lymphocyte Specific Protein 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Lymphocyte Specific Protein 1 antibody is available for research use only.

Storage Conditions

Aliquot the Lymphocyte Specific Protein 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Lymphocyte Specific Protein 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic, membrane

Image Legend

Western blot testing of human 1) Daudi and 2) Ramos cell lysate with Lymphocyte Specific Protein 1 antibody. Predicted molecular weight: ~37 kDa but is routinely observed at ~52 kDa (PMID: 15684321) .