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PRDX6 Antibody / Peroxiredoxin 6 / aiPLA2

PRDX6 is a member of the thiol-specific antioxidant protein family. This protein is a bifunctional enzyme with two distinct active sites. It is involved in redox regulation of the cell; it can reduce H (2) O (2) and short chain organic, fatty acid, and phospholipid hydroperoxides. It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:50-1:100, Western blot: 1:500-1:1000

UniProt

P30041

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 197-224 from the human protein was used as the immunogen for the PRDX6 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

FACS, IHC-P, WB

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the PRDX6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PRDX6 antibody is available for research use only.

Storage Conditions

Aliquot the PRDX6 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the PRDX6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

IHC testing of FFPE human brain tissue with PRDX6 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

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