ENPP2 Antibody / Autotaxin
ENPP2 functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This protein stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. This protein is secreted and further processed to make the biologically active form.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 1:25 (1x10e6 cells), Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:25
UniProt
Q13822
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 401-430 from the human protein was used as the immunogen for the ENPP2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, WB, IHC-P
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the ENPP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This ENPP2 antibody is available for research use only.
Storage Conditions
Aliquot the ENPP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Western blot testing of mouse cerebellum tissue lysate with ENPP2 antibody. Expected molecular weight: 99-125 kDa depending on glycosylation level.
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