RFC5 Antibody
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. RFC5 is the 36 kD subunit. This subunit can interact with the C-terminal region of PCNA. It forms a core complex with the 38 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system.
Product Specifications
UniProt
P40937
Host
Rabbit
Immunogen
A portion of amino acids 170-200 from the human protein was used as the immunogen for the RFC5 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, WB
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the RFC5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This RFC5 antibody is available for research use only.
CAS Number
9007-83-4
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