SUMO-activating enzyme subunit 1 Antibody / SAE1
The dimeric enzyme AOS1 acts as a an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins and formation of a thioester with a conserved cysteine residue on SAE2.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:1000, Immunohistochemistry (FFPE) : 1:25
UniProt
Q9UBE0
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 300-329 from the human protein was used as the immunogen for the SUMO-activating enzyme subunit 1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the SUMO-activating enzyme subunit 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This SUMO-activating enzyme subunit 1 antibody is available for research use only.
Storage Conditions
Aliquot the SUMO-activating enzyme subunit 1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Nuclear, cytoplasmic
Image Legend
Western blot testing of human HEK293 cell lysate with SUMO-activating enzyme subunit 1 antibody. Predicted molecular weight ~38 kDa.
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