USP2 Antibody
USP2, an ubiquitin-specific protease, is selectively up regulated in bone by the osteotropic agents PTH, PTHrP and PGE2 and possibly via the PKA/cAMP pathway. It is also thought to play a role in the recycling of ubiquitin by hydrolysis of branched poly-ubiquitin from linear poly-ubiquitin chains, production of free ubiquitin from linear poly-ubiquitin chains and from certain ribosomal ubiquitin fusion proteins.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1:50-1:100, Western blot: 1:1000-1:2000
UniProt
O75604
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 508-538 from the human protein was used as the immunogen for the USP2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, WB
Purity
Purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the USP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This USP2 antibody is available for research use only.
Storage Conditions
Aliquot the USP2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic, nuclear
Image Legend
IHC testing of FFPE human kidney tissue with USP2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Documents
Frequently Asked Questions
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