Cathepsin D Antibody / CTSD

Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Immunofluorescence: 1:25, Immunohistochemistry (FFPE) : 1:25

UniProt

P07339

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 1-412 from the human protein was used as the immunogen for the Cathepsin D antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IF, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Cathepsin D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Cathepsin D antibody is available for research use only.

Storage Conditions

Aliquot the Cathepsin D antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Cathepsin D antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

Western blot testing of human 1) A431, 2) MCF7, 3) K562 and 4) PANC-1 cell lysate with Cathepsin D antibody. Expected molecular weight: 43-46 kDa, 28 kDa (heavy chain), 15 kDa (light chain) .