TOPK Antibody / PBK
Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization (By similarity) . [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells)
UniProt
Q9JJ78
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 58-86 from the mouse protein was used as the immunogen for the TOPK antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, WB, FACS
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the TOPK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This TOPK antibody is available for research use only.
Storage Conditions
Aliquot the TOPK antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Nuclear
Image Legend
IHC testing of FFPE rat testis tissue with TOPK antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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