MAP2K1 Antibody / MEK1
The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000
UniProt
Q02750
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A portion of amino acids 200-227 from the human protein was used as the immunogen for the MAP2K1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, WB
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the MAP2K1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This MAP2K1 antibody is available for research use only.
Storage Conditions
Aliquot the MAP2K1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic, nuclear
Image Legend
Western blot testing of 1) human MDA-MB-231, 2) mouse NIH 3T3 and 3) rat C6 cell lysate with MAP2K1 antibody. Predicted molecular weight ~43 kDa.
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