ERLIN2 Antibody

Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) . Also involved in ITPR1 degradation by the ERAD pathway.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:1000

UniProt

O94905

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A portion of amino acids 307-333 from the human protein was used as the immunogen for the ERLIN2 antibody.

Clonality

Polyclonal

Isotype

Applications

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the ERLIN2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This ERLIN2 antibody is available for research use only.

Storage Conditions

Aliquot the ERLIN2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the ERLIN2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of 1) human 293T, 2) human A431, 3) mouse C2C12, 4) mouse NIH 3T3, 5) human breast and 6) human placenta lysate with ERLIN2 antibody. Predicted molecular weight: ~38 kDa, routinely observed at ~43 kDa.