Rubicon Antibody / RUBCN / BARON
Inhibits PIK3C3 activity; under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation. [UniProt]
Product Specifications
UniProt
Q92622
Host
Rabbit
Immunogen
A portion of amino acids 241-271 from the human protein was used as the immunogen for the Rubicon antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, FACS, IHC-P, IF
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Rubicon antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Rubicon antibody is available for research use only.
CAS Number
9007-83-4
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Rabbit anti-Arabidopsis thaliana (Mouse-ear cress) NFYC1 Polyclonal Antibody
