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PRRT2 Antibody

As a component of the outer core of AMPAR complex, Proline-rich transmembrane protein 2 may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca2+-sensing. In the cerebellum, may inhibit SNARE complex formation and downregulate short-term facilitation. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells)

UniProt

Q7Z6L0

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 207-233 from the human protein was used as the immunogen for the PRRT2 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, FACS

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the PRRT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PRRT2 antibody is available for research use only.

Storage Conditions

Aliquot the PRRT2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the PRRT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human brain tissue lysate with PRRT2 antibody. Predicted molecular weight ~35 kDa.

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