ALDH5A1 Antibody

ALDH5A1 belongs to the aldehyde dehydrogenase family of proteins. This protein functions as a mitochondrial NAD (+) -dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA) . In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000

UniProt

P51649

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 128-157 from the human protein was used as the immunogen for the ALDH5A1 antibody.

Clonality

Polyclonal

Isotype

Applications

IHC-P, WB

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the ALDH5A1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This ALDH5A1 antibody is available for research use only.

Storage Conditions

Aliquot the ALDH5A1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the ALDH5A1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.