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Phospholipase D2 Antibody / PLD2

Phosphatidylcholine (PC) -specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.[OMIM]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000

UniProt

O14939

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 10-39 from the human protein was used as the immunogen for the Phospholipase D2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Phospholipase D2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Phospholipase D2 antibody is available for research use only.

Storage Conditions

Aliquot the Phospholipase D2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Phospholipase D2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human MDA-MB-453 cell lysate with Phospholipase D2 antibody. Predicted molecular weight ~106 kDa.

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