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Map3k7 Antibody / Tak1

Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000

UniProt

Q62073

Host

Rabbit

Reactivity

Mouse

Immunogen

A portion of amino acids 131-160 from the mouse protein was used as the immunogen for the Map3k7 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC-P, WB

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Map3k7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Map3k7 antibody is available for research use only.

Storage Conditions

Aliquot the Map3k7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Map3k7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic, plasma membrane

Image Legend

IHC testing of FFPE mouse stomach tissue with Map3k7 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

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