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Plozasiran (sodium)

Plozasiran sodium is an siRNA targeting APOC3 for the study of mixed hyperlipidemia.

Product Specifications

CAS Number

2379776-41-5

Product Name Alternative

ARO-APOC3 (sodium)

UNSPSC

12352208

Target

Apolipoprotein

Type

Oligonucleotides

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/plozasiran-sodium.html

Purity

97.94

Smiles

[Plozasiran(sodium)]

Molecular Formula

C493H611F11N164Na43O311P43S7

Molecular Weight

15618.77 (free acid)

References & Citations

[1]Gaudet D, Pall D, Watts GF, et al. Plozasiran (ARO-APOC3) for Severe Hypertriglyceridemia: The SHASTA-2 Randomized Clinical Trial. JAMA Cardiol. 2024;9 (7) :620-630. |[2]Gaudet D, Clifton P, Sullivan D, et al. RNA Interference Therapy Targeting Apolipoprotein C-III in Hypertriglyceridemia. NEJM Evid. 2023;2 (12) :EVIDoa2200325.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Oligonucleotides

Clinical Information

Launched

Isoform

ApoC3

Available Sizes

Frequently Asked Questions

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