Plozasiran (sodium)
Plozasiran sodium is an siRNA targeting APOC3 for the study of mixed hyperlipidemia.
Product Specifications
CAS Number
[2379776-41-5]
Product Name Alternative
ARO-APOC3 (sodium)
UNSPSC
12352208
Target
Apolipoprotein
Type
Oligonucleotides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/plozasiran-sodium.html
Purity
97.94
Smiles
[Plozasiran(sodium)]
Molecular Formula
C493H611F11N164Na43O311P43S7
Molecular Weight
15618.77 (free acid)
References & Citations
[1]Gaudet D, Pall D, Watts GF, et al. Plozasiran (ARO-APOC3) for Severe Hypertriglyceridemia: The SHASTA-2 Randomized Clinical Trial. JAMA Cardiol. 2024;9 (7) :620-630. |[2]Gaudet D, Clifton P, Sullivan D, et al. RNA Interference Therapy Targeting Apolipoprotein C-III in Hypertriglyceridemia. NEJM Evid. 2023;2 (12) :EVIDoa2200325.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
Launched
Isoform
ApoC3
Available Sizes
Curated Selection
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