CalDAG-GEFI Antibody / RASGRP2
The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1:25, Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000
UniProt
Q7LDG7
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 7-34 from the human protein was used as the immunogen for the CalDAG-GEFI antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IF, IHC-P, WB
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the CalDAG-GEFI antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This CalDAG-GEFI antibody is available for research use only.
Storage Conditions
Aliquot the CalDAG-GEFI antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic
Image Legend
Western blot testing of human spleen tissue lysate with CalDAG-GEFI antibody. Predicted molecular weight ~69 kDa.
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